若生智能
Drug Database
RA

rabies vaccine

✓ Approved

Serum Institute of India Pvt. Ltd. · 疫苗 · 疫苗

什么是 rabies vaccine？

rabies vaccine 是一种疫苗，由Serum Institute of India Pvt. Ltd.研发。该药已获批，用于治疗相关适应症，给药途径：Injectable (Others)、Intradermal Injection、Intramuscular (IM) Injection。

药物档案

公司Serum Institute of India Pvt. Ltd.
药物类别疫苗, 大分子
给药途径Injectable (Others), Intradermal Injection, Intramuscular (IM) Injection
状态Approved
来源： ClinicalTrials.gov, Serum Institute of India Pvt. Ltd.

治疗适应症

rabies vaccine 针对 1 个适应症，涉及 1 个治疗领域。

治疗领域疾病/病症分期
Infections and infestationsRabies✓ Approved

相关研究文献

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Companion Animal Vaccine Hesitancy: Current Evidence and Practical Communication Strategies.

Hartley Ashley N AN, Ng Zenithson Z, Ludwig Claire E CE, Pritchard Jessica C JC

This review article summarizes the emergence of vaccine hesitancy in companion animal medicine and its parallels with human health care. Factors influencing pet owner vaccination decisions include concerns about safety, necessity, cost, overvaccination, and misinformation. Current literature suggests veterinarians remain the most trusted source of vaccine information and play a central role in maintaining vaccine confidence. The article reviews available data on companion animal vaccination trends, owner attitudes, and veterinary team perceptions while highlighting communication strategies, including motivational interviewing and presumptive recommendations, that may improve vaccine acceptance and strengthen preventive health care delivery.

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A systematic review of knowledge, attitudes, and behaviour towards Japanese encephalitis vaccination.

Nepali Rebika R, King Catherine C, Leask Julie J, Campbell Emma E et al.

Three billion people globally are at risk of Japanese Encephalitis (JE), a mosquito-borne disease primarily spread by Culex mosquitoes. Despite the availability of JE vaccine, uptake is limited and a deeper understanding of people's knowledge, attitudes, and behaviours (KABs) towards JE vaccine is needed to improve this. This study systematically reviewed the existing research on KABs towards JE vaccination, with a view to informing JE vaccine program delivery, policy and practice. Seven bibliometric databases, grey literature and references of included studies were searched for primary studies on KABs towards JE vaccination. Search outputs were independently screened; data were extracted and synthesised descriptively. Of the 26 studies included, most were conducted in JE endemic countries and examined four participant groups: travellers from non-endemic settings, caregivers of vaccine recipients and non-traveller adults from endemic settings, and vaccine providers/advocates from both settings. Of the few studies, adult vaccine recipients had low knowledge and awareness of the vaccine, whereas caregivers' knowledge and awareness were higher. Attitudes towards JE vaccination were generally positive and KABs were often influenced by health workers, community leaders, risk perception, cost, time constraints, migration, and vaccine availability and accessibility. There were limited KABs studies regarding JE vaccination using rigorous and consistent methodological approaches. This review highlights the barriers to JE vaccination and the role of health professionals and vaccine advocates in JE vaccination programs. Focusing on empowering these groups is key to increasing JE vaccine uptake across different populations.

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'I took the vaccine to protect myself': determinants of COVID-19 vaccine confidence in Indigenous communities in Northwest Territories, Canada.

Kolahdooz Fariba F, Zakkar Moutasem M, Manning Claire C, Omidimorad Afsaneh A et al.

Vaccine hesitancy is a persistent global health challenge. This project explored attitudes towards and utilization of COVID-19 vaccination, as well as suggestions to improve utilization within Indigenous communities in Northwest Territories, Canada. Utilizing a cross-sectional design, this project spanned two phases: 10 communities in Phase 1 (April to November 2021), and 11 in Phase 2 (August 2022-January 2023). Self-identifying Indigenous adults (≥18 years) were invited. Quantitative and qualitative data were collected via a semi-structured interviewer-administered questionnaire. In Phase 1 (n = 124; mean age = 41.6 years; 63.7% women) and Phase 2 (n = 221; mean age = 43.6 years; 66.21% women), 78.2% and 87.2% of participants had received at least one dose, respectively. In Phase 1, 67.2% reported not being concerned about the vaccine, and 61.2% believed the benefits outweighed the risks. In Phase 2, 56.2% of participants agreed all eligible individuals should be vaccinated, and 59.2% agreed the vaccine prevented serious outcomes. Bivariate analyses revealed that negative attitudes towards COVID-19 severity, vaccine safety, and effectiveness were significantly associated with lower intention to receive a COVID-19 vaccine in the future. Qualitative insights revealed factors of vaccination hesitancy, including: concerns about safety, efficacy, and necessity; a need for information; and distrust in government. Reasons for utilization included: trust in vaccine safety; perceived necessity; and employment and travel requirements. COVID-19 vaccine utilization in Indigenous communities is high, yet hesitancy persists due to safety and efficacy concerns, and distrust in government. Culturally safe strategies, improved communication, and equitable access are essential to sustaining confidence and future pandemic preparedness.

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Five values for COVID-19 vaccine acceptance described by racial and ethnic minoritized caregivers.

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Persistent racial and ethnic disparities in child COVID-19 vaccination rates in the US suggest that vaccinated racial and ethnic minoritized caregivers have hesitated to vaccinate their children. To address these disparities, we sought to understand perspectives on the COVID-19 vaccine among racial and ethnic minoritized caregivers of school-aged children. We recruited English, Spanish, and Haitian Creole-speaking caregivers of children ages 5-11 years-old seen for pediatric care at a safety-net hospital. We surveyed caregivers on vaccination status, demographics, and conducted semi-structured interviews regarding vaccine perception. We analyzed interviews using thematic analysis with grounded theory principles. We interviewed 20 caregivers (62% Non-Hispanic Black, 29% Hispanic). Caregivers had all received at least one vaccine dose and 62% of children were vaccinated against COVID-19. Caregivers discussed five core values used to appraise the COVID-19 vaccine: Safety, Knowledge, Trust, Humanity, and Autonomy. These five core values were used in decision-making about vaccination; ongoing appraisal of the vaccine after their own vaccination; and in consideration of the vaccine for their children. We conclude that public health campaigns attuned to these core values may be more accepting to families and help to reduce perpetuation of healthcare mistrust and persistent health disparities among racial and ethnic minoritized families.

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Mazibuko Lusanda L, Hoór Dorottya D, Nxumalo Vuyiswa V, Nxumalo Siyabonga S et al.

Trust in vaccines and those who deliver them is often shaped by personal social networks, yet empirical data on these dynamics remain limited in low-and middle-income settings. Social networks shape exposure to information, norms, and reinforcement processes that influence vaccine decision-making. We examined how rural South Africans' social network composition and content influence their willingness to receive a COVID-19 vaccine. We analysed 2022-23 data from the Sixhumene social network study conducted primarily among young adults in three rural KwaZulu-Natal communities. Our primary outcome was a six-level ordinal measure combining past vaccination and hypothetical willingness. Using multivariable ordinal logistic regression, we evaluated associations between vaccine willingness and social network size, kinship composition, geographic proximity, gender homophily, support received, and respondent characteristics. Respondents were predominantly female with median age 21 years (IQR 18-28) and identified a median of three key social contacts, with networks characterised by strong kinship and local ties. Vaccine willingness varied by the geographic composition of networks. Compared with urban respondents whose networks were concentrated within the household, willingness was higher among those with more geographically dispersed networks, including urban respondents with alters in the same village (aOR 2.54, 95% CI 2.40-2.70) or outside the village (aOR 3.26, 95% CI 2.04-5.20). Similarly, among rural respondents, willingness was higher among those with household-based networks (aOR 1.95, 95% CI 1.57-2.41), village-based networks (aOR 1.63, 95% CI 1.40-1.90), and networks extending beyond the village (aOR 1.64, 95% CI 1.50-1.79). Emotional support was positively associated with willingness (per 30 contact-days: aOR 1.15, 95% CI 1.01-1.32), while physical support was inversely associated (aOR 0.84, 95% CI 0.72-0.98). Vaccine willingness in this rural setting was shaped by both individual factors and network dynamics. Emotional support showed a modest positive association with willingness, suggesting supportive social ties may help promote vaccination willingness.

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